Research-tools

Castor is a platform-based or software-as-a-service data solution, enabling researchers to easily capture and integrate all data from any source, whether electronic or paper-based.

The UCSC Genome Browser is developed and maintained by the Genome Bioinformatics Group, a cross-departmental team within the UCSC Genomics Institute

PROVEAN (Protein Variation Effect Analyzer) is a software tool which predicts whether an amino acid substitution or indel has an impact on the biological function of a protein. PROVEAN is useful for filtering sequence variants to identify nonsynonymous or indel variants that are predicted to be functionally important. The performance of PROVEAN is comparable to popular tools such as SIFT or PolyPhen-2

PolyPhen-2 (Polymorphism Phenotyping v2) is a tool which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations

Pairwise Sequence Alignment is used to identify regions of similarity that may indicate functional, structural and/or evolutionary relationships between two biological sequences (protein or nucleic acid). By contrast, Multiple Sequence Alignment (MSA) is the alignment of three or more biological sequences of similar length. From the output of MSA applications, homology can be inferred and the evolutionary relationship between the sequences studied.

Multiple Sequence Alignment (MSA) is generally the alignment of three or more biological sequences (protein or nucleic acid) of similar length. From the output, homology can be inferred and the evolutionary relationships between the sequences studied.By contrast, Pairwise Sequence Alignment tools are used to identify regions of similarity that may indicate functional, structural and/or evolutionary relationships between two biological sequences.

It is an unincorporated collaboration among entities and individuals pursuing the common mission of accelerating progress in cerebral palsy genomic research. The consortium aims to achieve this goal by advancing a common infrastructure of genomics and clinical data, and harmonising approaches to enable effective and responsible sharing of genomics and health-related data.

providing knowledge resources on research writing, publishing in journals, and promotion of published work.

Symposia on research methodologies held at the I5th International Child Neurology Congress, Mumbai, India.

Top tips for writing a research paper from Bernard Dan, Editor of Developmental Medicine & Child Neurology